Human HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein (MHC-HM440T)
Catalogue Number: MHC-HM440T-KAT
MHC-HM440T Image
MHC-HM440T Image
MHC-HM440T Image
The purity of Human HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer is greater than 95% as determined by SEC-HPLC.
MHC-HM440T Image
Human HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer on Tris-Bis PAGE under Non reducing (N) condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
| Physical state: | Liquid |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
Description
Description: Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Additional Text
Gene Name
B2M
Uniprot ID
P61769
Protein Tag
HIS-AviTag™
Accession Number
AAV53343.1
Short Description
Recombinant Human HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGARGVGK peptide.
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
MHC-HM440T Datasheet
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