Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Protein (MHC-HM447T)
Catalogue Number: MHC-HM447T-KAT
MHC-HM447T Image
MHC-HM447T Image
MHC-HM447T Image
MHC-HM447T Image
The purity of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer is greater than 95% as determined by SEC-HPLC.
MHC-HM447T Image
Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
MHC-HM447T Image
Immobilized Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer, His Tag at 1µg/ml (100µl/well) on the plate. Dose response curve for Anti-HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
Additional Text
Gene Name
B2M
Gene ID
567
Uniprot ID
P61769
Protein Tag
HIS-AviTag™
Short Description
Recombinant Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and ALYVDSLFFL peptide.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
MHC-HM447T MSDS
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