PE-Labeled Human HLA-A*03:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer Protein (MHC-HM456TP)
Catalogue Number: MHC-HM456TP-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 6 months |
| Physical state: | Liquid |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
Description
Description: Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Additional Text
Gene Name
B2M
Gene ID
567
Uniprot ID
P61769
Accession Number
NP_002107.3
Protein Tag
HIS-AviTag™
Short Description
Recombinant PE-Labeled Human HLA-A*03:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*03:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin. It contains Gly25-Thr305 (HLA-A*03:01), Ile21-Met119 (B2M) and VVGAVGVGK peptide.
Storage Note
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
MHC-HM456TP MSDS
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations