LM11A-31 2HCI

Catalogue Number: N-3005-2-RPE

Manufacturer:rPeptide
Physical state:Pale Yellow Powder
Type:Ligand
Shipping Condition:RT
Unit(s): 25 mg

Description

Description: A nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-responsive cells1. Promotes functional recovery in a mouse model of spinal contusion injury2. Protects neurogenesis after traumatic brain injury3. Reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models4. Stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV-associated neuropathogenesis5. Orally active and blood-brain barrier permeant.