Catalogue Number: N-3017-1-RPE
Manufacturer: | rPeptide |
Physical state: | Lyophilized |
Type: | Other Inhibitors |
Shipping Condition: | RT |
Unit(s): | 10 mg |
Description: Antagonist of macrophage migration inhibitory factor (MIF, a pro-inflammatory cytokine). Displays anti-inflammatory activity. Increases survival in severe sepsis1. Inhibits airway remodeling in mouse asthma model2. Blocks MIF-induced autophagy3. Inhibits experimental autoimmune diabetes in a mouse model, reducing islet antigen-specific proliferative responses and adhesive cell-cell interactions4. Active in cellular and mouse models. Reverses Amyloid Beta-induced toxicity in mouse and human neuronal cell lines5.