IOS-1

Catalogue Number: N-3017-1-RPE

Manufacturer:rPeptide
Physical state:Lyophilized
Type:Other Inhibitors
Shipping Condition:RT
Unit(s): 10 mg

Description

Description: Antagonist of macrophage migration inhibitory factor (MIF, a pro-inflammatory cytokine). Displays anti-inflammatory activity. Increases survival in severe sepsis1. Inhibits airway remodeling in mouse asthma model2. Blocks MIF-induced autophagy3. Inhibits experimental autoimmune diabetes in a mouse model, reducing islet antigen-specific proliferative responses and adhesive cell-cell interactions4. Active in cellular and mouse models. Reverses Amyloid Beta-induced toxicity in mouse and human neuronal cell lines5.