Catalogue Number: N-3028-1-RPE
Manufacturer: | rPeptide |
Physical state: | Powder |
Type: | Other Inhibitors |
Shipping Condition: | RT |
Unit(s): | 50 mg |
Description: Potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM)1,2. Displays anti-inflammatory and anti-asthmatic effects. Clinically useful agent for treatment of chronic asthma3. Attenuates chronic brain injury after focal cerebral ischemia in rodent models4. Decreases blood brain barrier dysfunction in mouse models5. Blockade of GPR17 by montelukast elevates neural stem and progenitor proliferation6.