Catalogue Number: N-3029-2-RPE
Manufacturer: | rPeptide |
Physical state: | white crystalline powder |
Type: | Other Inhibitors |
Shipping Condition: | RT |
Unit(s): | 25 mg |
Description: Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP)1. Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage2. Inhibits MPTP opening and protects neurons from apoptosis3. Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model4.