Induces Dimerization of c-Met and Exerts Biological Activity similar to HGF
*This is for illustrative purpose.
PG-001 Image 2
We performed a functional comparison test between our HGF Alternative Peptide (PG-001) and commercially available recombinant HGF.
From the results, PG-001 showed the property which promotes the phosphorylation of c-Met receptor and the proliferation of HUVEC at the same level per molecule compared with recombinant HGF.
The molecular weight of HGF Alternative peptide is approximately 4.7kDa, which is approximately 16 times smaller than that of recombinant HGF.
PG-001 Image 3
We performed a functional comparison test between our HGF Alternative Peptide (PG-001) and commercially available recombinant HGF.
From the results, PG-001 showed the property which promotes the phosphorylation of c-Met receptor and the proliferation of HUVEC at the same level per molecule compared with recombinant HGF.
The molecular weight of HGF Alternative peptide is approximately 4.7kDa, which is approximately 16 times smaller than that of recombinant HGF.
PG-001 Image 4
Applications Data
Professor Hideki Taniguchi at the Institute of Medical Science, University of Tokyo conducted proliferation and cloning tests of liver cells derived from induced pluripotent stem cells (iPS cells) using recombinant HGF or PG-001. As a result, it was confirmed that PG-001 has activity equivalent to HGF at the same level.