Catalogue Number: PR-101-JEN
Manufacturer: | Jena Bioscience |
Shelf Life: | 12 months |
Molecular Weight: | α: 44 kDa, β: 38 kDa |
Physical state: | Liquid |
Type: | Transferases |
Shipping Condition: | Dry Ice |
Unit(s): | 50 ug |
Description: GGTase-I (Geranylgeranyltransferase-I) catalyzes the transfer of the farnesyl and geranylgeranyl groups from farnesyl and geranylgeranyl-diphosphate to proteins containing a C-terminal CaaX motif, where 'C' is a conserved cysteine that is the site of farnesyl modification, 'a' is usually an aliphatic amino acid, and 'X' is leucine or phenylalanine. Farnesyltransferase (FT) and GGTase-I are closely related, sharing a common α subunit and 30% identity in their β subunits.
NM_031082
α- and β-subunit