Catalogue Number: PR-215-JEN
Manufacturer: | Jena Bioscience |
Shelf Life: | 12 months |
Molecular Weight: | 24.0 kDa (216 amino acids) |
Physical state: | Liquid |
Type: | Other Enzymes |
Shipping Condition: | Dry Ice |
Unit(s): | 50 ug |
Description: Ran (Ras-related nuclear protein, TC4) belongs to the Ras superfamily of GTP binding proteins. It acts in cellular processes such as nuclear transport, mitotic spindle assembly, and post-mitotic nuclear assembly. The mutation E70A results in inhibition of the guanine exchange reaction mediated by RCC1, the guanine nucleotide exchange factor (GEF) for Ran. Protein preparation is 85% GDP-loaded, measured by HPLC.
NM_006325