RafRBD (c-Raf), Ras Binding Domain of Raf, c-Raf 1 Kinase, human, recombinant, E. coli

Catalogue Number: PR-305-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Weight:9.4 kDa (50 - 132 amino acids)
Physical state:Liquid
Type:Protein Kinases
Shipping Condition:Dry Ice
Unit(s): 50 ug

Description

Description: Raf is a member of the serine/threonine proteine kinase family involved in regulation of cell growth and differentiation and is the most important effector of Ras. Full-length Raf is composed of three conserved regions responsible for interaction with Ras, for phosphorylation and for catalytic activity. RafRBD (Ras binding domain, amino acids 50-132) mediates interaction with membrane-anchored Ras necessary for activation of the kinase activity of Raf.

Additional Text

Gene ID

5894

Gene Name

RAF1

Uniprot ID

P04049

Accession Number

X03484