Catalogue Number: S0322-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Shipping Condition: | Blue Ice |
Unit(s): | 25 mg, 5 mg |
Description: BC-1215 is an inhibitor of F-box protein 3 (Fbxo3, a ubiquitin E3 ligase component)with IC50 of 0.9 µg/mL and LC50 of 87 µg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.