BC-1215
Catalogue Number: S0322-SEL
| Manufacturer: | Selleck Chemicals |
| Molecular Formula: | C26H26N4 |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg |
Additional Text
Short Description
BC-1215 is an inhibitor of F-box protein 3 (Fbxo3, a ubiquitin E3 ligase component) with IC50 of 0.9 µg/mL and LC50 of 87 µg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.
Smile String
C1=CC=NC(=C1)C2=CC=C(C=C2)CNCCNCC3=CC=C(C=C3)C4=CC=CC=N4
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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