Methotrexate
Catalogue Number: S1210-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C20H22N8O5 |
| Type: | Other Inhibitors |
| Alias: | NCI-C04671, Amethopterin, CL14377, WR19039 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 500 mg, 10 mM/ 1 mL, 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
Smile String
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Short Description
Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.
Storage Note
3 years -20°C(in the dark) powder1 year -80°C(in the dark) in solvent
Inhibitor Handling Instructions
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