Catalogue Number: S1264-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Alias: | PD173074 |
Shipping Condition: | Blue Ice |
Unit(s): | 5 mg, 50 mg, 10 mM/ 1 mL, 1 g |
Description: PD173074 is a potent FGFR1inhibitor with IC50of ~25 nM and also inhibits VEGFR2with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosisin gastric cancer cells.
FOR RESEARCH USE ONLY