Catalogue Number: S1288-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Alias: | Camptothecin |
Shipping Condition: | Blue Ice |
Unit(s): | 100 mg, 500 mg, 10mM (1mL in DMSO), 1 g |
Description: Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I)with IC50of 0.68 µM in a cell-free assay. Camptothecin induces apoptosisin cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
FOR RESEARCH USE ONLY