Quizartinib (AC220)
Catalogue Number: S1526-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg, 50 mg, 10 mM/ 1 mL |
Description
Description: Quizartinib (AC220) is a second-generation FLT3inhibitor for Flt3(ITD/WT)with IC50of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosisof tumor cells. Phase 3.
Additional Text
Caution
FOR RESEARCH USE ONLY
S1526 MSDS
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