Quizartinib (AC220)

Catalogue Number: S1526-SEL

Manufacturer:Selleck Chemicals
Shelf Life:24 months
Molecular Formula:C29H32N6O4S
Type:Other Inhibitors
Shipping Condition:Blue Ice
Unit(s): 5 mg, 50 mg, 10 mM/ 1 mL

Additional Text

Caution

FOR RESEARCH USE ONLY

Smile String

CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3

Short Description

Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.

Storage Note

2 years -80 in solvent

Price
£161.00


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