Catalogue Number: S1567-SEL
Manufacturer: | Selleck Chemicals |
Type: | Ligand |
Alias: | Pomalidomide |
Shipping Condition: | Blue Ice |
Unit(s): | 50 mg, 10 mM/ 1 mL, 200 mg, 1 g |
Description: Pomalidomide inhibits LPS-induced TNF-αrelease with IC50of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligaseand inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosisand cell cycle arrest.
FOR RESEARCH USE ONLY
19171-19-8