Catalogue Number: S1680-SEL
Manufacturer: | Selleck Chemicals |
Shelf Life: | 24 months |
Molecular Formula: | C10H20N2S4 |
Type: | Enzyme Inhibitors |
Alias: | NSC 190940, Tetraethylthiuram disulfide, TETD |
Shipping Condition: | Blue Ice |
Unit(s): | 10 mM/ 1 mL, 1 g, 500 mg, 50 mg |
FOR RESEARCH USE ONLY
CCN(CC)C(=S)SSC(=S)N(CC)CC
Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH) with IC50 of 0.15 µM and 1.45 µM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD).
2 years -80 in solvent