Catalogue Number: S1680-SEL
Manufacturer: | Selleck Chemicals |
Type: | Enzyme Inhibitors |
Alias: | Disulfiram |
Shipping Condition: | Blue Ice |
Unit(s): | 10 mM/ 1 mL, 1 g, 500 mg, 50 mg |
Description: Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH)with IC50 of 0.15 µM and 1.45 µM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD).
FOR RESEARCH USE ONLY