PF-3716556

Catalogue Number: S2222-SEL

Manufacturer:Selleck Chemicals
Shelf Life:24 months
Molecular Formula:C22H26N4O3
Type:Other Inhibitors
Shipping Condition:Blue Ice
Unit(s): 10 mg

Additional Text

Caution

FOR RESEARCH USE ONLY

Short Description

PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+,K+-ATPase, used for the treatment of gastroesophageal reflux disease.

Smile String

CC1=C2C(CCOC2=CC=C1)NC3=CC(=CN4C3=NC(=C4)C)C(=O)N(C)CCO

Storage Note

2 years -80 in solvent