Catalogue Number: S2286-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Alias: | Cyclosporin A |
Shipping Condition: | Blue Ice |
Unit(s): | 50 mg, 10 mM/ 1 mL, 200 mg, 1 g |
Description: Cyclosporin A, a non-polar cyclic oligopeptide, is an immunosuppressive agent that binds to cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay. Cyclosporin A is generally given following transplant surgery to prevent rejection and has been used to test its toxic effect on a perfused 3D proximal tubule model.
FOR RESEARCH USE ONLY