Catalogue Number: S2680-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Shipping Condition: | Blue Ice |
Unit(s): | 5 mg, 50 mg, 10 mM/ 1 mL, 200 mg, 1 g |
Description: Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk)inhibitor with IC50of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACsincluding P13I.
FOR RESEARCH USE ONLY