Catalogue Number: S2777-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Alias: | PF-5274857 |
Shipping Condition: | Blue Ice |
Unit(s): | 5 mg |
Description: PF-5274857 is a potent and selective Smoothened (Smo)antagonist, inhibits Hedgehog(Hh) signaling with IC50and Kiof 5.8 nM and 4.6 nM, respectively, and can penetrate the blood-brain barrier.
FOR RESEARCH USE ONLY