PF-5274857

Catalogue Number: S2777-SEL

Manufacturer:Selleck Chemicals
Type:Other Inhibitors
Alias:PF-5274857
Shipping Condition:Blue Ice
Unit(s): 5 mg

Description

Description: PF-5274857 is a potent and selective Smoothened (Smo)antagonist, inhibits Hedgehog(Hh) signaling with IC50and Kiof 5.8 nM and 4.6 nM, respectively, and can penetrate the blood-brain barrier.

Additional Text

Caution

FOR RESEARCH USE ONLY