Carfilzomib (PR-171)

Catalogue Number: S2853-SEL

Manufacturer:Selleck Chemicals
Type:Other Inhibitors
Shipping Condition:Blue Ice
Unit(s): 5 mg, 50 mg, 10 mM/ 1 mL, 200 mg, 1 g

Description

Description: Carfilzomib (PR-171) is an irreversible proteasomeinhibitor with IC50of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagyand induces cell apoptosis.

Additional Text

Caution

FOR RESEARCH USE ONLY

Price
£139.00


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