Triptolide
Catalogue Number: S3604-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 5 mg, 10 mM/1 ml, 1 g, 100 mg |
Description
Description: Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κBinhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2and induces apoptosisthrough a p53-independent pathway.
Additional Text
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FOR RESEARCH USE ONLY
S3604 MSDS
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