Harmine hydrochloride
Catalogue Number: S3817-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C13H12N2O.HCl |
| Type: | Other Inhibitors |
| Alias: | Telepathine hydrochloride |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 10 mM/1 ml, 1 g |
Additional Text
Short Description
Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.
Smile String
CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC.Cl
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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