Catalogue Number: S6962-SEL
Manufacturer: | Selleck Chemicals |
Type: | Biochemicals |
Shipping Condition: | Blue Ice |
Unit(s): | 25 mg, 1 g |
Description: TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosisin NB4 cells via negatively regulating intracellular NOand Zn2+signaling. TPEN (TPEDA) may be a potential therapeutic strategy for APL (acute promyelocytic leukemia).TPEN induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.