Catalogue Number: S7046-SEL
Manufacturer: | Selleck Chemicals |
Type: | Enzyme Inhibitors |
Alias: | Brefeldin A |
Shipping Condition: | Blue Ice |
Unit(s): | 100 mg, 25 mg, 5 mg, 10 mM/ 1 mL, 1 g |
Description: Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transportwith IC50of 0.2 µM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagyand mitophagy.
FOR RESEARCH USE ONLY