(+)-JQ1
Catalogue Number: S7110-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Biochemicals |
| Alias: | (+)-JQ1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 mg, 25 mg, 10mM (1mL in DMSO), 100 mg, 1 g |
Description
Description: (+)-JQ1 is a BET bromodomaininhibitor, with IC50of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3)target genes.
Additional Text
Caution
FOR RESEARCH USE ONLY
S7110 MSDS
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