Trabectedin
Catalogue Number: S7758-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
Description
Description: Trabectedin (Ecteinascidin 743, ET-743) is a marine alkaloid isolated from the Caribbean tunicate Ecteinascidia turbinata with antitumouractivity. Trabectedin binds to the N2 of guanine in the minor groove, causing DNA damage and affecting transcription regulation in a promoter- and gene-specific manner.
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