A1874

Catalogue Number: S8785-SEL

Manufacturer:Selleck Chemicals
Molecular Formula:C58H62Cl3F2N9O7S
Type:Biochemicals
Shipping Condition:Blue Ice
Unit(s): 1 mg, 5 mg

Additional Text

Short Description

A1874 is a much improved nutlin-based, BRD4-degrading PROTAC and is able to degrade its target protein by 98% with nanomolar potency.

Smile String

CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCOCCOCCOCCNC(=O)C4=CC(=C(C=C4)NC(=O)C5C(C(C(N5)CC(C)(C)C)(C#N)C6=C(C=C(C=C6)Cl)F)C7=C(C(=CC=C7)Cl)F)OC)C8=CC=C(C=C8)Cl)C

Storage Note

3 years -20°C powder