Catalogue Number: S8785-SEL
Manufacturer: | Selleck Chemicals |
Molecular Formula: | C58H62Cl3F2N9O7S |
Type: | Biochemicals |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 5 mg |
A1874 is a much improved nutlin-based, BRD4-degrading PROTAC and is able to degrade its target protein by 98% with nanomolar potency.
CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCOCCOCCOCCNC(=O)C4=CC(=C(C=C4)NC(=O)C5C(C(C(N5)CC(C)(C)C)(C#N)C6=C(C=C(C=C6)Cl)F)C7=C(C(=CC=C7)Cl)F)OC)C8=CC=C(C=C8)Cl)C
3 years -20°C powder