GMB-475
Catalogue Number: S8888-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg, 25 mg, 10 mM/1 ml |
Description
Description: GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1protein and recruit the E3 ligaseVon Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.
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