Actinomycin D (Dactinomycin)
Catalogue Number: S8964-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 mg, 50 mg, 1 g, 100 mg |
Description
Description: Actinomycin D (Dactinomycin, Act D, RASP-101) is a significant polypeptide antibiotic isolated from soil bacteria of the genus Streptomyces. Actinomycin D (Dactinomycin) inhibits DNA repairand rests the cell cycleat G1 phase with IC50 of 0.42 µM and 0.4 nM, respectively. Actinomycin D is an autophagyactivator, induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
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