Catalogue Number: SA-3001-2-RPE
Manufacturer: | rPeptide |
Type: | Monoclonal Primary Antibody - Unconjugated |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg |
Host name: | |
Clone: | 10C3 |
Isotype: | |
Immunogen: |
Description: Alpha-Synuclein (α-Synuclein) is a 14 kD (140 amino acids) acidic presynaptic protein. It is a major component of Parkinson's disease aggregates and is implicated in the pathogenesis of Parkinson's Disease and related neurodegenerative disorders. α-Synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson's disease. α-Synuclein appears to associate with other proteins that aggregate and is found in β-amyloid plaques and neuritic tangles in Alzheimer's disease. Alpha Synuclein 10C3 is a monoclonal antibody that is specific for human alpha synuclein. 10C3 has been shown to work within ELISA, Western Blot, as well as Immunhistochemistry experiments.
Monoclonal