Catalogue Number: BSM-52497R-BSS
Manufacturer: | Bioss Inc |
Shelf Life: | 12 months |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Cytochrome c, CYCS |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Rabbit |
Clone: | 8D2 |
Isotype: | IgG |
Immunogen: | Full length protein |
Application: | ICC, IF, IHC-P, WB |
Description: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
CYCS
54205
P99999
Protein A purified
1 ug/ul
Monoclonal
Unmodified
Store at -20°C for 12 months.