The endoplasmic reticulum (ER) is an organelle present in most eukaryotic cells. It is primarily responsible for the synthesis and transport of cellular products such as proteins, lipids and hormones. Structurally, the ER is comprised of an interconnected network of flattened, membrane-enclosed sacs and tubules that extend from the nuclear membrane throughout the cytoplasm. These sac-like structure and tubules are held together and supported by the cytoskeleton.