Gold Nanorods

Cytodiagnostics carboxyl functionalized gold nanorods have precisely engineered surface chemistry that enables coupling to various moieties that react with carboxylic acids. One of the most popular applications of this interaction is EDC/NHS coupling. The EDC activates the carboxylic acid so that it can react with NHS and acquire new functionality. The introduction of the NHS group then allows it to react with primary amines, which enables covalent coupling to proteins and antibodies with exposed amine-containing residues such as lysine. This permanent linkage has thus provided a gold nanoparticle label to the molecule in question and allows easier monitoring and localization within cells.

Cytodiagnostics carboxyl gold nanorods are available in 3 different aspect ratios, with absorption maxima of 650nm, 700nm or 770nm, and are also available with 2 different spacer lengths (3 kDa and 5 kDa). This provides the customer with the necessary tools fully optimize their experiment.

Cytodiagnostics amine functionalized gold nanorods have precisely engineered surface chemistry that allows for simple and efficient binding to moieties that react with primary amines. An example of such a reaction would be a conjugation to a protein or antibody that has been tagged NHS, which would yield a covalent link between the gold nanoparticle surface and the protein. This permanent linkage allows for further downstream applications such as monitoring the distribution of the now-tagged molecule.

Cytodiagnostics amine gold nanorods are available with 3 different aspect ratios, with maxima of 650nm, 700nm, or 770nm, and are also available with 2 different spacer lengths (3 kDa and 5 kDa). This provides the customer with the necessary tools to fully optimize their experiment.

Cytodiagnostics methoxy gold nanorods have precisely engineered surface chemistry that renders them inert in most applications. This inert property allows these nanorods to be used as excellent control samples when in combination with one of our other functionalized nanorods. In applications where the nanorods are not being used as controls, the surface chemistry enables them to be used in solutions with much higher salt concentrations.
Cytodiagnostics methoxy gold nanorods are available in 3 different aspect ratios, with absorption maxima of 650nm, 700nm or 770nm, and are also available with 2 different spacer lengths (2 kDa and 5 kDa), allowing for better optimization.