Metabolism Assay Kits Research Areas

Oxidative stress refers to the imbalance of the production and elimination of oxygen free radicals in the body or cells, which leads to the accumulation of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in vivo or cells, resulting in oxidative damage. A large number of studies have shown that oxidative stress causes the occurrence and development of a variety of diseases (see the chart below).

There are two kinds of antioxidant system, one is enzyme antioxidant system, including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and so on. The other is non-enzymatic antioxidant system, including ergothioneine, vitamin C, vitamin E, glutathione, melatonin, α-lipoic acid, carotenoid, trace element copper, zinc, selenium (Se) and so on.

Elabscience^® has developed a series of metabolism assays for ROS, RNS, Glutathione GSH and Anti-oxidation, covering a wide range of indicators related to oxidative stress to meet your research needs.

The main functions of the liver include detoxification, metabolism, bile secretion, hemopoietic blood storage and regulation of circulating blood volume, immune defense and regeneration. The indicators of liver biomarkers are mainly divided into four categories, as shown in the following chart：

1. Hepatocyte injury: serum alanine aminotransferase (ALT), serum glutamic-oxaloacetic aminotransferase (AST), alkaline phosphatase (ALP), γ-glutamyl transpeptidase (γ-GT), lactate dehydrogenase (LDH), etc.

Elabscience^® offers a variety of metabolism assay kits related to liver biomarkers research to meet your research needs.

Kidney function refers to the function of kidney excreting metabolic waste, maintaining the stability of sodium, potassium, calcium and other electrolytes and the function of acid-base balance. The changes of creatinine clearance rate, serum creatinine and blood urea nitrogen can be used to determine the normality or impairment degree of the kidney function. For example, when chronic kidney function is impaired, the creatinine clearance rate is decreased. While the serum creatinine is still within the normal range, which is a mild impairment of kidney function. If serum creatinine also increased, it is moderate damage.

Elabscience^® offers a variety of metabolism assay kits related to amino acid & proteins research to meet your experiment needs.

Elabscience^® provides key indicators for glycolytic processes, including glycogen, glucose, pyruvate, lactic acid and other glucide, which can make great help for your monitor and study of glycolytic processes.

Inorganic ions account for only 1-1.5% of fresh weight in biological cells, but are closely related to life activities and indispensable. Abnormal concentrations of inorganic ions can cause diseases. Iron deficiency can cause anemia, low immunity, fatigue, etc. Iron excess can cause heart failure, cirrhosis, etc. Zinc deficiency can cause anorexia, ulcer, cirrhosis, dwarfism, etc. Zinc excess can cause gastroenteritis, hypertension, coronary heart disease, etc.

Lipids metabolism is an important and complex biochemical reaction in the body, it refers to the digestion, absorption, synthesis and decomposition process of fat with the help of a variety of related enzymes. During this process, the fat then be processed into substance needed by the body to ensure the operation of normal physiological functions. It is of great significance to the activities of life. The process can be summarized as following chart:

I am text block. Click edit button to change this text. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

Elabscience® has carefully collected metabolism assay kits related to lipids metabolism research, click on the link to see the details.

In order to meet the needs of researchers for rapid detection of material content and enzyme activity, Elabscience® provides you with metabolism assay kits for the detection of various metabolic indicators produced by plants during adversity stress. Our metabolism assay kits are easy to operate and have strong repeatability, which can save time and promote efficient.

There are many plant-related factors in the environment, and they are in dynamic change. Plants have certain tolerance limits to each factor. Once the environmental factors change beyond this tolerance limit, there will be environment stress. After a long period of stress exercise, plants have evolved a series of mechanisms to resist adverse environments, which is the resistance of plants to environment stress. These stresses can lead to metabolic changes in plants, resulting in changes in the contents of reactive oxygen species, proline and secondary metabolites. Plant stress resistance is mainly used in cold-resistant, hot-acclimation, breeding screening of resistant plant varieties and so on.

The TCA cycle takes place in the mitochondria of the cell. Decarboxylation and dehydrogenation of pyruvate are carried out by TCA cycle. The carboxyl group formed into CO₂. The hydrogen atoms formed into H₂O and release ATP under the oxidative phosphorylation with the NAD⁺ and FAD as carrier. In addition, TCA cycle is also a common pathway for oxidative decomposition of various fuel molecules, such as fatty acids and amino acids. The cycle begins with the condensation of acetyl coenzyme A with oxaloacetic acid to form Citric acid, which is catalyzed by citrate synthetase. Disorder of the TCA cycle, whether caused by disease state or sub-healthy body, can lead to a wide range of metabolic disorders and diseases. The TCA cycle can be described as follows: